CDS

Accession Number TCMCG011C17981
gbkey CDS
Protein Id XP_021903150.1
Location join(38285..38689,40487..40768,40849..40996,41388..41473,42559..42636,42756..42845)
Gene LOC110818552
GeneID 110818552
Organism Carica papaya

Protein

Length 362aa
Molecule type protein
Topology linear
Data_file_division PLN
dblink BioProject:PRJNA264084
db_source XM_022047458.1
Definition COP9 signalosome complex subunit 5a [Carica papaya]

EGGNOG-MAPPER Annotation

COG_category OT
Description protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of the CSN complex (By similarity). The CSN complex is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. The complex is also required for degradation of PSIAA6 by regulating the activity of the Ubl ligase SCF-TIR complex. Involved in CSN's deneddylation derubylation activity. Required for the deneddylation of all cullins. Essential for the structural integrity of the CSN holocomplex
KEGG_TC -
KEGG_Module -
KEGG_Reaction -
KEGG_rclass -
BRITE ko00000        [VIEW IN KEGG]
ko01000        [VIEW IN KEGG]
ko01002        [VIEW IN KEGG]
ko04121        [VIEW IN KEGG]
KEGG_ko ko:K09613        [VIEW IN KEGG]
EC -
KEGG_Pathway -
GOs GO:0000003        [VIEW IN EMBL-EBI]
GO:0000338        [VIEW IN EMBL-EBI]
GO:0003002        [VIEW IN EMBL-EBI]
GO:0003006        [VIEW IN EMBL-EBI]
GO:0006109        [VIEW IN EMBL-EBI]
GO:0006464        [VIEW IN EMBL-EBI]
GO:0006508        [VIEW IN EMBL-EBI]
GO:0006807        [VIEW IN EMBL-EBI]
GO:0007275        [VIEW IN EMBL-EBI]
GO:0007346        [VIEW IN EMBL-EBI]
GO:0007389        [VIEW IN EMBL-EBI]
GO:0008150        [VIEW IN EMBL-EBI]
GO:0008152        [VIEW IN EMBL-EBI]
GO:0009653        [VIEW IN EMBL-EBI]
GO:0009719        [VIEW IN EMBL-EBI]
GO:0009725        [VIEW IN EMBL-EBI]
GO:0009733        [VIEW IN EMBL-EBI]
GO:0009791        [VIEW IN EMBL-EBI]
GO:0009889        [VIEW IN EMBL-EBI]
GO:0009893        [VIEW IN EMBL-EBI]
GO:0009894        [VIEW IN EMBL-EBI]
GO:0009896        [VIEW IN EMBL-EBI]
GO:0009908        [VIEW IN EMBL-EBI]
GO:0009987        [VIEW IN EMBL-EBI]
GO:0010033        [VIEW IN EMBL-EBI]
GO:0010093        [VIEW IN EMBL-EBI]
GO:0010099        [VIEW IN EMBL-EBI]
GO:0010100        [VIEW IN EMBL-EBI]
GO:0010387        [VIEW IN EMBL-EBI]
GO:0010389        [VIEW IN EMBL-EBI]
GO:0010564        [VIEW IN EMBL-EBI]
GO:0010565        [VIEW IN EMBL-EBI]
GO:0010604        [VIEW IN EMBL-EBI]
GO:0010971        [VIEW IN EMBL-EBI]
GO:0016043        [VIEW IN EMBL-EBI]
GO:0019222        [VIEW IN EMBL-EBI]
GO:0019538        [VIEW IN EMBL-EBI]
GO:0022414        [VIEW IN EMBL-EBI]
GO:0022607        [VIEW IN EMBL-EBI]
GO:0030656        [VIEW IN EMBL-EBI]
GO:0031323        [VIEW IN EMBL-EBI]
GO:0031326        [VIEW IN EMBL-EBI]
GO:0031347        [VIEW IN EMBL-EBI]
GO:0032501        [VIEW IN EMBL-EBI]
GO:0032502        [VIEW IN EMBL-EBI]
GO:0034622        [VIEW IN EMBL-EBI]
GO:0036211        [VIEW IN EMBL-EBI]
GO:0042176        [VIEW IN EMBL-EBI]
GO:0042221        [VIEW IN EMBL-EBI]
GO:0043170        [VIEW IN EMBL-EBI]
GO:0043255        [VIEW IN EMBL-EBI]
GO:0043412        [VIEW IN EMBL-EBI]
GO:0043933        [VIEW IN EMBL-EBI]
GO:0044085        [VIEW IN EMBL-EBI]
GO:0044237        [VIEW IN EMBL-EBI]
GO:0044238        [VIEW IN EMBL-EBI]
GO:0044260        [VIEW IN EMBL-EBI]
GO:0044267        [VIEW IN EMBL-EBI]
GO:0045732        [VIEW IN EMBL-EBI]
GO:0045787        [VIEW IN EMBL-EBI]
GO:0045931        [VIEW IN EMBL-EBI]
GO:0048367        [VIEW IN EMBL-EBI]
GO:0048437        [VIEW IN EMBL-EBI]
GO:0048444        [VIEW IN EMBL-EBI]
GO:0048449        [VIEW IN EMBL-EBI]
GO:0048518        [VIEW IN EMBL-EBI]
GO:0048519        [VIEW IN EMBL-EBI]
GO:0048522        [VIEW IN EMBL-EBI]
GO:0048580        [VIEW IN EMBL-EBI]
GO:0048581        [VIEW IN EMBL-EBI]
GO:0048583        [VIEW IN EMBL-EBI]
GO:0048585        [VIEW IN EMBL-EBI]
GO:0048608        [VIEW IN EMBL-EBI]
GO:0048646        [VIEW IN EMBL-EBI]
GO:0048731        [VIEW IN EMBL-EBI]
GO:0048856        [VIEW IN EMBL-EBI]
GO:0050789        [VIEW IN EMBL-EBI]
GO:0050793        [VIEW IN EMBL-EBI]
GO:0050794        [VIEW IN EMBL-EBI]
GO:0050896        [VIEW IN EMBL-EBI]
GO:0051093        [VIEW IN EMBL-EBI]
GO:0051171        [VIEW IN EMBL-EBI]
GO:0051173        [VIEW IN EMBL-EBI]
GO:0051193        [VIEW IN EMBL-EBI]
GO:0051196        [VIEW IN EMBL-EBI]
GO:0051239        [VIEW IN EMBL-EBI]
GO:0051241        [VIEW IN EMBL-EBI]
GO:0051246        [VIEW IN EMBL-EBI]
GO:0051247        [VIEW IN EMBL-EBI]
GO:0051726        [VIEW IN EMBL-EBI]
GO:0060255        [VIEW IN EMBL-EBI]
GO:0061458        [VIEW IN EMBL-EBI]
GO:0062012        [VIEW IN EMBL-EBI]
GO:0065003        [VIEW IN EMBL-EBI]
GO:0065007        [VIEW IN EMBL-EBI]
GO:0070646        [VIEW IN EMBL-EBI]
GO:0070647        [VIEW IN EMBL-EBI]
GO:0071704        [VIEW IN EMBL-EBI]
GO:0071840        [VIEW IN EMBL-EBI]
GO:0080090        [VIEW IN EMBL-EBI]
GO:0080134        [VIEW IN EMBL-EBI]
GO:0090068        [VIEW IN EMBL-EBI]
GO:0090567        [VIEW IN EMBL-EBI]
GO:0090696        [VIEW IN EMBL-EBI]
GO:0090697        [VIEW IN EMBL-EBI]
GO:0090698        [VIEW IN EMBL-EBI]
GO:0090701        [VIEW IN EMBL-EBI]
GO:0099402        [VIEW IN EMBL-EBI]
GO:1901564        [VIEW IN EMBL-EBI]
GO:1901987        [VIEW IN EMBL-EBI]
GO:1901989        [VIEW IN EMBL-EBI]
GO:1901990        [VIEW IN EMBL-EBI]
GO:1901992        [VIEW IN EMBL-EBI]
GO:1902749        [VIEW IN EMBL-EBI]
GO:1902751        [VIEW IN EMBL-EBI]
GO:1905392        [VIEW IN EMBL-EBI]
GO:1905393        [VIEW IN EMBL-EBI]
GO:2000026        [VIEW IN EMBL-EBI]
GO:2000030        [VIEW IN EMBL-EBI]
GO:2000082        [VIEW IN EMBL-EBI]

Sequence

CDS:  
ATGGAGCCTAATCCATCGTCGTCATCTTCTTCGCTAATCGCCCAGCAAACATGGGAACTTGAGAACAATATACTGCCGATGGAGCCACCGGACCTGTCGTCTGATTCAATCTTCTACTACGACGAGGCTGGCCAGGGAAAGTTCCAGCAAGAGAAGCCTTGGGCCAACGATCCTCACTACTTTAAGCGCGTCAAGATCTCCGCACTCGCCCTCCTCAAGATGGTCGTCCACGCACGCTCCGGTGGGACCATCGAGGTCATGGGCCTTATGCAGGGCAAGACCGACGGTGACGCCATCATCGTTATGGATGCTTTTGCTCTCCCTGTCGAAGGCACCGAGACTAGGGTTAATGCCCAGGCTGATGCCTATGAGTACATGGTCGAATATTCTCAAACCAATAAGCTGGCTGGACGGTTAGAGAATGTCGTTGGTTGGTATCATTCACATCCTGGATACGGATGCTGGCTTTCTGGAATTGATGTTTCAACACAAATGCTCAACCAGCAATTTCAGGAGCCCTTCTTAGCTGTTGTTATTGATCCAACAAGGACTGTTTCAGCTGGGAAAGTTGAGATTGGGGCATTCAGGACATATCCAGAAGGATATAAGCCTCCAGATGATCCTGTCTCTGAGTATCAGACAATTCCTCTGAATAAGATTGAAGACTTTGGAGTGCATTGTAAACAGTATTATGCATTGGATATCACTTATTTTAAGTCCTCTCTTGATTGTCACCTTCTGGATTTGCTTTGGAACAAGTACTGGGTGAATACACTTTCATCTTCACCTTTATTGGGTAATGGAGACTATGTTGCTGGTCAAATTTCCGACTTAGCTGAGAAGCTGGAGCAAGCAGAGAATCAACTGGCTCACTCCAGGTTGGGTGGAATAGTGCCAGGACCTTTTCAAAGAAAGAAAGAGGAAGAATCTCAACTTGCAAAGATCACTCGAGACAGTGCAAAGATAACTGTGGAGCAGGTCCATGGACTAATGTCACAGGTTATCAAGGACATCCTTTTCAACTCTGTCCGTCAGTCAAACAGATCTCGCTGTGAGGTGTCTGGCCCCGAGCCAATGATTGAAGCATGA
Protein:  
MEPNPSSSSSSLIAQQTWELENNILPMEPPDLSSDSIFYYDEAGQGKFQQEKPWANDPHYFKRVKISALALLKMVVHARSGGTIEVMGLMQGKTDGDAIIVMDAFALPVEGTETRVNAQADAYEYMVEYSQTNKLAGRLENVVGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFLAVVIDPTRTVSAGKVEIGAFRTYPEGYKPPDDPVSEYQTIPLNKIEDFGVHCKQYYALDITYFKSSLDCHLLDLLWNKYWVNTLSSSPLLGNGDYVAGQISDLAEKLEQAENQLAHSRLGGIVPGPFQRKKEEESQLAKITRDSAKITVEQVHGLMSQVIKDILFNSVRQSNRSRCEVSGPEPMIEA